Lucas Sapienza, MD, PhD, is an Assistant Professor in the Department of Radiation Oncology at the University of Florida. Dr. Sapienza is originally from Brazil and joined UF after completing residency training at the Department of Radiation Oncology at Baylor College of Medicine in Houston, TX. He specializes in advanced radiation techniques including image-guided adaptive brachytherapy, proton therapy, and radiosurgery for treatment of gynecological cancers, breast cancer and prostate cancer.
Dr. Sapienza has led two prospective clinical trials as the principal investigator (NCT01925651 and NCT02091050) and is the lead author of 22 research studies published in peer-reviewed journals, including the International Journal of Radiation Oncology Biology Physics, Gynecologic Oncology, Brachytherapy, International Journal of Gynecological Cancer, Clinical and Translational Radiation Oncology and Urology.
During his radiation oncology training in Brazil (2012-2015) and the United States (2020-2024), Dr. Sapienza has received multiple awards, including The Brentani’s Prize (First Place + research grant) from the Fundação Antonio Prudente/A. C. Camargo Cancer Center in 2014 and The Roentgen Resident/Fellow Research Award from the Radiological Society of North America Research & Education Foundation in 2023.
Residency – Radiation Oncology
Baylor College of Medicine, Houston, TX
Transitional Internship
Ascension Providence Hospital – Michigan State University, Southfield, MI
PhD – Radiation Oncology (Gynecological Brachytherapy)
A.C. Camargo Cancer Center, São Paulo, SP, Brazil
Residency – Radiation Oncology
A.C. Camargo Cancer Center, São Paulo, SP, Brazil
Medical Degree
Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil
English | Portuguese
Dr. Sapienza focuses on brachytherapy technique development to improve disease control and reduce pelvic radiation toxicity. His research addresses urinary tract damage, intra-operative uterine perforation, and post-treatment pelvic insufficiency fractures. He also excels in advanced statistical analysis methods, including various methods of quantitative data synthesis (meta-analyses).
The Roentgen Resident/Fellow Research Award
Radiological Society of North America (RSNA) Research & Education Foundation (2023)
7th Annual Department of Radiation Oncology Research Symposium - Excellence in Research - Second Place Presentation
Baylor College of Medicine (2022)
6th Annual Department of Radiation Oncology Research Symposium - Excellence in Research - Second Place Presentation
Baylor College of Medicine (2021)
6th Annual Department of Radiation Oncology Research Symposium - Outstanding Contribution to the Symposium
Baylor College of Medicine (2021)
3rd Brazilian Varian Scientific Competition – First Place 2014
Congresso da Sociedade Brasileira de Radioterapia (SBRT) (2014)
Brentani’s Prize – First Place for Best Clinical Study
Fundação Antonio Prudente/A. C. Camargo Cancer Center (2014)
1st Latin American Varian Scientific Competition – First Place 2014
Congreso da Asociación Ibero Latinoamericana de Terapia Radiante Oncológica (ALATRO) (2013)
ENEM 2005 (National Exam for University Admission) – National First Place
Colégio de São Bento (2005)
It is the opportunity to collaborate with excellent professionals across all the areas of the department, providing high-quality patient care, optimize resources and actively contribute to advancements in the field through more individualized and effective treatments.