1st Study title:
PCG BRE009-23: Phase III Randomized Trial of Conventionally Fractionated vs. Hypofractionated COMprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning PROton Therapy (COMPRO)
Principal Investigator:
Julie Bradley, MD, MHCDS
Why is this study being done?
The purpose of this research study is to learn more about the effects of using proton radiation therapy delivered over a shorter course of treatment (3 weeks) compared with a longer, standard course of treatment (5 weeks) for women with breast cancer who require radiotherapy to the breast/chest wall and regional lymph nodes.
Contact us for additional Information on this trial.
There are no Central Nervous System clinical trials open for enrollment at this time.
There are no Chordomas and/or Chondrosarcomas clinical trials open for enrollment at this time.
Study title:
UF-HN-004: Risk Adapted De-Intensification of Radio-Chemotherapy for Favorable Prognosis Oropharyngeal Squamous Cell Carcinoma based on HPV subtype and plasma circulating free HPV DNA Level and Clearance Rate.
Principal Investigator:
Roi Dagan, MD, MS
Why is this study being done?
Prior research shows that most people with HPV (Human papillomavirus) -related Oropharyngeal squamous cell carcinoma (OPSCC) have a substance called cell-free HPV DNA (cfHPV DNA) in their blood. In addition to the detectability of cfHPV, this study explores the notion that lower doses of radiation therapy may be as effective as the standard higher doses used presently. This could result in fewer side effects with apparent equal effectiveness against these types of head & neck cancer.
There are no lung cancer clinical trials open for enrollment at this time.
There are no Lymphoma clinical trials open for enrollment at this time.
Study title:
The University of Florida Health Proton Therapy Institute (UFHPTI) Radiation Oncology Outcome Tracking Project (RADTRAC-JAX)
Principal Investigator:
Nancy P. Mendenhall, MD
Why is this study being done?
The purpose of this study is to collect information from you and your medical records regarding your disease, your treatment, and your side effects to see what effects the radiation has on you and your disease.
Contact us for additional Information on this trial.
Study title:
PAN009-18 (PC04): A Phase II Trial of Escalated Dose Proton Radiotherapy with Elective Nodal Irradiation and Concomitant Chemotherapy for Patients with Unresectable, Borderline Resectable or Medically Inoperable Pancreatic Adenocarcinoma
Principal Investigator:
R. Charles Nichols, MD
Why is this study being done?
The purpose of this study is to find out what effects, good and/or bad, proton radiation combined with chemotherapy and surgery, if performed, has on you and your pancreatic cancer. The goal is improved disease free survival. This study will look at the side effects from the treatment and the quality of your life in relation to your treatment experience. It will also look at how the tumor responds to the combination of treatment with proton radiation.
Contact us for additional Information on this trial.
1st Study title:
Proton and Photon Consortium Registry (PPCR)
Local Principal Investigator:
Daniel J. Indelicato, MD
Why is this study being done?
The purpose of this registry is to collect demographic information (like age, race, gender, zip code) and clinical data (such as diagnosis, treatments and side effects) of pediatric patients who receive proton therapy.
Contact us for additional Information on this trial.
1st Study title:
GU010-18 (PR06): Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy
Principal Investigator:
Randal H. Henderson, MD, MBA
Why is this study being done?
The purpose of this study is to evaluate the safety and effectiveness of proton radiation therapy for patients who have undergone radical prostatectomy.
Contact us for additional Information on this trial.
2nd Study title:
UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for in-vivo Proton Treatment Monitoring in Pencil-Beam Scanning
Principal Investigator:
Jiyeon Park, PhD
Why is this study being done?
The purpose of this study is to evaluate the use of ionizing-radiation photo acoustic imaging (iRAI) for proton radiation treatment. Ionizing-radiation photo acoustic imaging (iRAI) is a method of collecting images from inside the body using acoustic (sound) waves. We will collect iRAI during your radiation treatments.
Contact us for additional Information on this trial.
3rd Study title:
UCCC 20-1684: A pilot study evaluating the effect of 2D antiscatter grids on CBCT image quality
Principal Investigator:
Perry Johnson, PhD
Why is this study being done?
ENROLLMENT COMING SOON. The purpose of this study is to see if the quality of computed tomography (CT) images taken during your radiation treatment sessions could be improved using a two-dimensional (2D) antiscatter grid, a type of x-ray filter. Improved image quality may allow clinicians to see tumors and healthy tissues better to deliver radiation more accurately
Contact us for additional Information on this trial.
There are no Sarcoma clinical trials open for enrollment at this time.
There are no Skin clinical trials open for enrollment at this time.
